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Integrin α(IIb)β3: A novel effector of Gα(13)

Under physiological conditions, circulating platelets are discoid in shape.1 On these platelets, the fibrinogen receptor (integrin α(IIb)β(3)) is in a low-affinity state, unable to bind soluble fibrinogen (Fg). Activation by agonists such as ADP and thrombin leads to a change in the conformation of...

詳細記述

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書誌詳細
主要な著者: Chari-Turaga, Ramya, Naik, Ulhas P
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038087/
https://ncbi.nlm.nih.gov/pubmed/20930548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cam.5.1.13559
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