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Binding of CIB1 to the α(IIb) tail of α(IIb)β(3) is required for FAK recruitment and activation in platelets
BACKGROUND: It is believed that activation of c-Src bound to the integrin β(3) subunit initiates outside-in signaling. The involvement of α(IIb) in outside-in signaling is poorly understood. OBJECTIVES: We have previously shown that CIB1 specifically interacts with the cytoplasmic domain of α(IIb) a...
Zapisane w:
| Wydane w: | PLoS One |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2017
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5443481/ https://ncbi.nlm.nih.gov/pubmed/28542214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176602 |
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