JAM-A protects from thrombosis by suppressing integrin α(IIb)β(3)-dependent outside-in signaling in platelets

Mounting evidence suggests that agonist-initiated signaling in platelets is closely regulated to avoid excessive responses to injury. A variety of physiologic agonists induce a cascade of signaling events termed as inside-out signaling that culminate in exposure of high-affinity binding sites on int...

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Detaylı Bibliyografya
Asıl Yazarlar: Naik, Meghna U., Stalker, Timothy J., Brass, Lawrence F., Naik, Ulhas P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2012
Konular:
Platelets and Thrombopoiesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3321861/
https://ncbi.nlm.nih.gov/pubmed/22271446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-397398
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