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JAM-A protects from thrombosis by suppressing integrin α(IIb)β(3)-dependent outside-in signaling in platelets
Mounting evidence suggests that agonist-initiated signaling in platelets is closely regulated to avoid excessive responses to injury. A variety of physiologic agonists induce a cascade of signaling events termed as inside-out signaling that culminate in exposure of high-affinity binding sites on int...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Hematology
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3321861/ https://ncbi.nlm.nih.gov/pubmed/22271446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-397398 |
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