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Dual Effects of IκB Kinase β-Mediated Phosphorylation on p105 Fate: SCF(β-TrCP)-Dependent Degradation and SCF(β-TrCP)-Independent Processing

Processing of the p105 NF-κB precursor to yield the p50 active subunit is a unique and rare case in which the ubiquitin system is involved in limited processing rather than in complete destruction of its target. The mechanisms involved in this process are largely unknown, although a glycine repeat i...

詳細記述

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書誌詳細
主要な著者: Cohen, Shai, Achbert-Weiner, Hillit, Ciechanover, Aaron
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC303339/
https://ncbi.nlm.nih.gov/pubmed/14673179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.475-486.2004
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