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Dual Effects of IκB Kinase β-Mediated Phosphorylation on p105 Fate: SCF(β-TrCP)-Dependent Degradation and SCF(β-TrCP)-Independent Processing

Processing of the p105 NF-κB precursor to yield the p50 active subunit is a unique and rare case in which the ubiquitin system is involved in limited processing rather than in complete destruction of its target. The mechanisms involved in this process are largely unknown, although a glycine repeat i...

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書目詳細資料
發表在:Mol Cell Biol
Principais autores: Cohen, Shai, Achbert-Weiner, Hillit, Ciechanover, Aaron
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2004
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303339/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673179/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.475-486.2004
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