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Dual Effects of IκB Kinase β-Mediated Phosphorylation on p105 Fate: SCF(β-TrCP)-Dependent Degradation and SCF(β-TrCP)-Independent Processing

Processing of the p105 NF-κB precursor to yield the p50 active subunit is a unique and rare case in which the ubiquitin system is involved in limited processing rather than in complete destruction of its target. The mechanisms involved in this process are largely unknown, although a glycine repeat i...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Principais autores: Cohen, Shai, Achbert-Weiner, Hillit, Ciechanover, Aaron
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2004
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303339/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673179/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.475-486.2004
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