Dual Effects of IκB Kinase β-Mediated Phosphorylation on p105 Fate: SCF(β-TrCP)-Dependent Degradation and SCF(β-TrCP)-Independent Processing

Processing of the p105 NF-κB precursor to yield the p50 active subunit is a unique and rare case in which the ubiquitin system is involved in limited processing rather than in complete destruction of its target. The mechanisms involved in this process are largely unknown, although a glycine repeat i...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Cohen, Shai, Achbert-Weiner, Hillit, Ciechanover, Aaron
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2004
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303339/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14673179/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.1.475-486.2004
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