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Dual Effects of IκB Kinase β-Mediated Phosphorylation on p105 Fate: SCF(β-TrCP)-Dependent Degradation and SCF(β-TrCP)-Independent Processing

Processing of the p105 NF-κB precursor to yield the p50 active subunit is a unique and rare case in which the ubiquitin system is involved in limited processing rather than in complete destruction of its target. The mechanisms involved in this process are largely unknown, although a glycine repeat i...

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Bibliografiska uppgifter
Huvudupphovsmän: Cohen, Shai, Achbert-Weiner, Hillit, Ciechanover, Aaron
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2004
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC303339/
https://ncbi.nlm.nih.gov/pubmed/14673179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.1.475-486.2004
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