The Presence of a vpu Gene and the Lack of Nef-Mediated Downmodulation of T Cell Receptor-CD3 Are Not Always Linked in Primate Lentiviruses

Nef is an accessory protein critical for the ability of human and simian immunodeficiency viruses (HIV and SIV) to replicate efficiently in their respective hosts. Previous analyses of members of 15 different primate lentivirus lineages revealed a link between Nef function and the presence of a vpu...

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Dades bibliogràfiques
Autors principals: Schmökel, Jan, Sauter, Daniel, Schindler, Michael, Leendertz, Fabian H., Bailes, Elizabeth, Dazza, Marie-Christine, Saragosti, Sentob, Bibollet-Ruche, Frederic, Peeters, Martine, Hahn, Beatrice H., Kirchhoff, Frank
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020008/
https://ncbi.nlm.nih.gov/pubmed/21068258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02087-10
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