Nef-Mediated Enhancement of Virion Infectivity and Stimulation of Viral Replication Are Fundamental Properties of Primate Lentiviruses

Nef is a multifunctional accessory protein of primate lentiviruses. Recently, it has been shown that the ability of Nef to downmodulate CD4, CD28, and class I major histocompatibility complex is highly conserved between most or all primate lentiviruses, whereas Nef-mediated downregulation of T-cell...

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Detalhes bibliográficos
Main Authors: Münch, Jan, Rajan, Devi, Schindler, Michael, Specht, Anke, Rücker, Elke, Novembre, Francis J., Nerrienet, Eric, Müller-Trutwin, Michaela C., Peeters, Martine, Hahn, Beatrice H., Kirchhoff, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168858/
https://ncbi.nlm.nih.gov/pubmed/17928336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00904-07
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