The Presence of a vpu Gene and the Lack of Nef-Mediated Downmodulation of T Cell Receptor-CD3 Are Not Always Linked in Primate Lentiviruses

Nef is an accessory protein critical for the ability of human and simian immunodeficiency viruses (HIV and SIV) to replicate efficiently in their respective hosts. Previous analyses of members of 15 different primate lentivirus lineages revealed a link between Nef function and the presence of a vpu...

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Dettagli Bibliografici
Autori principali: Schmökel, Jan, Sauter, Daniel, Schindler, Michael, Leendertz, Fabian H., Bailes, Elizabeth, Dazza, Marie-Christine, Saragosti, Sentob, Bibollet-Ruche, Frederic, Peeters, Martine, Hahn, Beatrice H., Kirchhoff, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2011
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020008/
https://ncbi.nlm.nih.gov/pubmed/21068258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02087-10
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