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Nef Proteins from Diverse Groups of Primate Lentiviruses Downmodulate CXCR4 To Inhibit Migration to the Chemokine Stromal Derived Factor 1

Nef proteins of primate lentiviruses promote viral replication, virion infectivity, and evasion of antiviral immune responses by modulating signal transduction pathways and downregulating expression of receptors at the cell surface that are important for efficient antigen-specific responses, such as...

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Autors principals: Hrecka, Kasia, Swigut, Tomek, Schindler, Michael, Kirchhoff, Frank, Skowronski, Jacek
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182621/
https://ncbi.nlm.nih.gov/pubmed/16051857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.16.10650-10659.2005
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