The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu function

BACKGROUND: The acquisition of effective Vpu-mediated anti-tetherin activity to promote virion release following transmission of SIVcpzPtt from central chimpanzees (Pan troglodytes troglodytes) to humans distinguishes pandemic HIV-1 group M strains from non-pandemic group N, O and P viruses and may...

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Hlavní autoři: Kluge, Silvia F, Sauter, Daniel, Vogl, Michael, Peeters, Martine, Li, Yingying, Bibollet-Ruche, Frederic, Hahn, Beatrice H, Kirchhoff, Frank
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621411/
https://ncbi.nlm.nih.gov/pubmed/23514615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-32
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