Efficient Vpu-Mediated Tetherin Antagonism by an HIV-1 Group O Strain

Simian immunodeficiency viruses (SIVs) use their Nef proteins to counteract the restriction factor tetherin. However, a deletion in human tetherin prevents antagonism by the Nef proteins of SIVcpz and SIVgor, which represent the ape precursors of human immunodeficiency virus type 1 (HIV-1). To promo...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Mack, Katharina, Starz, Kathrin, Sauter, Daniel, Langer, Simon, Bibollet-Ruche, Frederic, Learn, Gerald H., Stürzel, Christina M., Leoz, Marie, Plantier, Jean-Christophe, Geyer, Matthias, Hahn, Beatrice H., Kirchhoff, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331793/
https://ncbi.nlm.nih.gov/pubmed/28077643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02177-16
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