Nef Proteins of Epidemic HIV-1 Group O Strains Antagonize Human Tetherin

Most simian immunodeficiency viruses use their Nef protein to antagonize the host restriction factor tetherin. A deletion in human tetherin confers Nef resistance, representing a hurdle to successful zoonotic transmission. HIV-1 group M evolved to utilize the viral protein U (Vpu) to counteract teth...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Host Microbe
Prif Awduron: Kluge, Silvia F., Mack, Katharina, Iyer, Shilpa S., Pujol, François M., Heigele, Anke, Learn, Gerald H., Usmani, Shariq M., Sauter, Daniel, Joas, Simone, Hotter, Dominik, Bibollet-Ruche, Frederic, Plenderleith, Lindsey J., Peeters, Martine, Geyer, Matthias, Sharp, Paul M., Fackler, Oliver T., Hahn, Beatrice H., Kirchhoff, Frank
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274627/
https://ncbi.nlm.nih.gov/pubmed/25525794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.10.002
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