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Comparison of amyloid fibril formation by two closely related immunoglobulin light chain variable domains
Light chain amyloidosis (AL amyloidosis) is a hematological disorder in which a clonal population of B cells expands and secretes enormous amounts of the immunoglobulin light chain protein. These light chains misfold and aggregate into amyloid fibrils, leading to organ dysfunction and death. We have...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018850/ https://ncbi.nlm.nih.gov/pubmed/21077798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13506129.2010.530081 |
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