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Comparison of amyloid fibril formation by two closely related immunoglobulin light chain variable domains

Light chain amyloidosis (AL amyloidosis) is a hematological disorder in which a clonal population of B cells expands and secretes enormous amounts of the immunoglobulin light chain protein. These light chains misfold and aggregate into amyloid fibrils, leading to organ dysfunction and death. We have...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Martin, Douglas J., Ramirez-Alvarado, Marina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018850/
https://ncbi.nlm.nih.gov/pubmed/21077798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13506129.2010.530081
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