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Comparison of amyloid fibril formation by two closely related immunoglobulin light chain variable domains

Light chain amyloidosis (AL amyloidosis) is a hematological disorder in which a clonal population of B cells expands and secretes enormous amounts of the immunoglobulin light chain protein. These light chains misfold and aggregate into amyloid fibrils, leading to organ dysfunction and death. We have...

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Main Authors: Martin, Douglas J., Ramirez-Alvarado, Marina
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018850/
https://ncbi.nlm.nih.gov/pubmed/21077798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/13506129.2010.530081
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