IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children’s Oncology Group

PURPOSE: Recent studies have demonstrated a high frequency of IDH mutations in adult “secondary” malignant gliomas arising from preexisting lower grade lesions, often in young adults, but not in “primary” gliomas. Because pediatric malignant gliomas share some molecular features with adult secondary...

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Détails bibliographiques
Auteurs principaux: Pollack, Ian F., Hamilton, Ronald L., Sobol, Robert W., Nikiforova, Marina N., Lyons-Weiler, Maureen A., LaFramboise, William A., Burger, Peter C., Brat, Daniel J., Rosenblum, Marc K., Holmes, Emiko J., Zhou, Tianni, Jakacki, Regina I.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014378/
https://ncbi.nlm.nih.gov/pubmed/20725730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00381-010-1264-1
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