IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children’s Oncology Group

PURPOSE: Recent studies have demonstrated a high frequency of IDH mutations in adult “secondary” malignant gliomas arising from preexisting lower grade lesions, often in young adults, but not in “primary” gliomas. Because pediatric malignant gliomas share some molecular features with adult secondary...

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Detalhes bibliográficos
Main Authors: Pollack, Ian F., Hamilton, Ronald L., Sobol, Robert W., Nikiforova, Marina N., Lyons-Weiler, Maureen A., LaFramboise, William A., Burger, Peter C., Brat, Daniel J., Rosenblum, Marc K., Holmes, Emiko J., Zhou, Tianni, Jakacki, Regina I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014378/
https://ncbi.nlm.nih.gov/pubmed/20725730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00381-010-1264-1
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