Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: a report of the Children's Oncology Group ACNS0423 study

BACKGROUND: The prognosis for children with malignant glioma is poor. This study was designed to determine whether lomustine and temozolomide following radiotherapy and concurrent temozolomide improves event-free survival (EFS) compared with historical controls with anaplastic astrocytoma (AA) or gl...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Jakacki, Regina I., Cohen, Kenneth J., Buxton, Allen, Krailo, Mark D., Burger, Peter C., Rosenblum, Marc K., Brat, Daniel J., Hamilton, Ronald L., Eckel, Sandrah P., Zhou, Tianni, Lavey, Robert S., Pollack, Ian F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Clinical Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035517/
https://ncbi.nlm.nih.gov/pubmed/27006176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now038
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