Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group

To determine whether temozolomide is an active agent in the treatment of children with high-grade astrocytomas and whether survival is influenced by the expression of the O6-methylguanine-methyltransferase gene (MGMT) in these patients. In the Children's Oncology Group study ACNS0126, 107 patie...

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Autores principales: Cohen, Kenneth J., Pollack, Ian F., Zhou, Tianni, Buxton, Allen, Holmes, Emiko J., Burger, Peter C., Brat, Daniel J., Rosenblum, Marc K., Hamilton, Ronald L., Lavey, Robert S., Heideman, Richard L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
Materias:
Clinical Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064602/
https://ncbi.nlm.nih.gov/pubmed/21339192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq191
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