Temozolomide in the treatment of high-grade gliomas in children: a report from the Children's Oncology Group

To determine whether temozolomide is an active agent in the treatment of children with high-grade astrocytomas and whether survival is influenced by the expression of the O6-methylguanine-methyltransferase gene (MGMT) in these patients. In the Children's Oncology Group study ACNS0126, 107 patie...

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Autori principali: Cohen, Kenneth J., Pollack, Ian F., Zhou, Tianni, Buxton, Allen, Holmes, Emiko J., Burger, Peter C., Brat, Daniel J., Rosenblum, Marc K., Hamilton, Ronald L., Lavey, Robert S., Heideman, Richard L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
Soggetti:
Clinical Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064602/
https://ncbi.nlm.nih.gov/pubmed/21339192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq191
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