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Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase

Every polyketide synthase module has an acyl carrier protein (ACP) and a ketosynthase (KS) domain that collaborate to catalyze chain elongation. The same ACP then engages the KS domain of the next module to facilitate chain transfer. Understanding the mechanism for this orderly progress of the growi...

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Detalles Bibliográficos
Main Authors: Kapur, Shiven, Chen, Alice Y., Cane, David E., Khosla, Chaitan
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009775/
https://ncbi.nlm.nih.gov/pubmed/21127271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014081107
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