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Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase

Every polyketide synthase module has an acyl carrier protein (ACP) and a ketosynthase (KS) domain that collaborate to catalyze chain elongation. The same ACP then engages the KS domain of the next module to facilitate chain transfer. Understanding the mechanism for this orderly progress of the growi...

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Détails bibliographiques
Auteurs principaux: Kapur, Shiven, Chen, Alice Y., Cane, David E., Khosla, Chaitan
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009775/
https://ncbi.nlm.nih.gov/pubmed/21127271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014081107
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