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Molecular recognition between ketosynthase and acyl carrier protein domains of the 6-deoxyerythronolide B synthase

Every polyketide synthase module has an acyl carrier protein (ACP) and a ketosynthase (KS) domain that collaborate to catalyze chain elongation. The same ACP then engages the KS domain of the next module to facilitate chain transfer. Understanding the mechanism for this orderly progress of the growi...

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書目詳細資料
Main Authors: Kapur, Shiven, Chen, Alice Y., Cane, David E., Khosla, Chaitan
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009775/
https://ncbi.nlm.nih.gov/pubmed/21127271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014081107
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