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Insulin Detemir is Not Transported Across the Blood-Brain Barrier

Insulin detemir has a different profile of action on the central nervous system (CNS) than human insulin. It has been hypothesized that this is caused by an altered ability of insulin detemir to cross the blood-brain barrier (BBB). Here, we measured the permeability of the BBB to insulin detemir. We...

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Bibliographische Detailangaben
Hauptverfasser: Banks, William A., Morley, John E., Lynch, Jessica L., Lynch, Kristin M., Mooradian, Arshag D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006236/
https://ncbi.nlm.nih.gov/pubmed/20868713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.09.011
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