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Insulin Detemir is Not Transported Across the Blood-Brain Barrier

Insulin detemir has a different profile of action on the central nervous system (CNS) than human insulin. It has been hypothesized that this is caused by an altered ability of insulin detemir to cross the blood-brain barrier (BBB). Here, we measured the permeability of the BBB to insulin detemir. We...

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Bibliographic Details
Main Authors: Banks, William A., Morley, John E., Lynch, Jessica L., Lynch, Kristin M., Mooradian, Arshag D.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006236/
https://ncbi.nlm.nih.gov/pubmed/20868713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.09.011
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