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Transport across the Blood-Brain Barrier of Pluronic Leptin

Leptin is a peptide hormone produced primarily by adipose tissue that acts as a major regulator of food intake and energy homeostasis. Impaired transport of leptin across the blood-brain barrier (BBB) contributes to leptin resistance, which is a cause of obesity. Leptin as a candidate for the treatm...

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Autors principals: Price, Tulin O., Farr, Susan A., Yi, Xiang, Vinogradov, Serguei, Batrakova, Elena, Banks, William A., Kabanov, Alexander V.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846026/
https://ncbi.nlm.nih.gov/pubmed/20053933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.158147
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