Intranasal Delivery of N-terminal Modified Leptin-Pluronic Conjugate for Treatment of Obesity

Leptin is an adipocyte-secreted hormone that is delivered via a specific transport system across the blood-brain barrier (BBB) to the brain where it acts on the hypothalamus receptors to control appetite and thermogenesis. Peripheral resistance to leptin due to its impaired brain delivery prevents t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Yuan, Dongfen, Yi, Xiang, Zhao, Yuling, Poon, Chi-Duen, Bullock, Kristin M., Hansen, Kim M., Salameh, Therese. S., Farr, Susan A., Banks, William A., Kabanov, Alexander V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603367/
https://ncbi.nlm.nih.gov/pubmed/28344017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.03.029
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados