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Insulin Detemir is Not Transported Across the Blood-Brain Barrier

Insulin detemir has a different profile of action on the central nervous system (CNS) than human insulin. It has been hypothesized that this is caused by an altered ability of insulin detemir to cross the blood-brain barrier (BBB). Here, we measured the permeability of the BBB to insulin detemir. We...

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Библиографические подробности
Главные авторы: Banks, William A., Morley, John E., Lynch, Jessica L., Lynch, Kristin M., Mooradian, Arshag D.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006236/
https://ncbi.nlm.nih.gov/pubmed/20868713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.09.011
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