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Insulin Detemir is Not Transported Across the Blood-Brain Barrier

Insulin detemir has a different profile of action on the central nervous system (CNS) than human insulin. It has been hypothesized that this is caused by an altered ability of insulin detemir to cross the blood-brain barrier (BBB). Here, we measured the permeability of the BBB to insulin detemir. We...

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Detalhes bibliográficos
Main Authors: Banks, William A., Morley, John E., Lynch, Jessica L., Lynch, Kristin M., Mooradian, Arshag D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006236/
https://ncbi.nlm.nih.gov/pubmed/20868713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.09.011
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