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Insulin transport across the blood–brain barrier can occur independently of the insulin receptor

KEY POINTS: Insulin enters the brain from the blood via a saturable transport system. It is unclear how insulin is transported across the blood–brain barrier (BBB). Using two models of the signalling‐related insulin receptor loss or inhibition, we show insulin transport can occur in vivo without the...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Rhea, Elizabeth M., Rask‐Madsen, Christian, Banks, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166047/
https://ncbi.nlm.nih.gov/pubmed/30044494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276149
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