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Insulin transport across the blood–brain barrier can occur independently of the insulin receptor

KEY POINTS: Insulin enters the brain from the blood via a saturable transport system. It is unclear how insulin is transported across the blood–brain barrier (BBB). Using two models of the signalling‐related insulin receptor loss or inhibition, we show insulin transport can occur in vivo without the...

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Dades bibliogràfiques
Publicat a:J Physiol
Autors principals: Rhea, Elizabeth M., Rask‐Madsen, Christian, Banks, William A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166047/
https://ncbi.nlm.nih.gov/pubmed/30044494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP276149
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