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How punctual ablation of Foxp3(+) T cells unleashes an autoimmune lesion within the pancreatic islets

CD4(+)Foxp3(+) regulatory T cells (Tregs) are known to control the progression of autoimmune diabetes, but when, where and how they exert their influence in this context are questions still under vigorous debate. Exploiting a transgene encoding the human diphtheria toxin receptor, we punctually and...

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Bibliografski detalji
Glavni autori: Feuerer, Markus, Shen, Yuelei, Littman, Dan R, Benoist, Christophe, Mathis, Diane
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998796/
https://ncbi.nlm.nih.gov/pubmed/19818653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.08.023
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