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Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity

In both human patients and murine models, the progression from insulitis to diabetes is neither immediate nor inevitable, as illustrated by the innocuous versus destructive infiltrates of BDC2.5 transgenic mice on the nonobese diabetic (NOD) versus C57BL/6.H-2(g(7)) genetic backgrounds. Natural kill...

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Détails bibliographiques
Auteurs principaux: Poirot, Laurent, Benoist, Christophe, Mathis, Diane
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC419564/
https://ncbi.nlm.nih.gov/pubmed/15141080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402065101
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