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Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity

In both human patients and murine models, the progression from insulitis to diabetes is neither immediate nor inevitable, as illustrated by the innocuous versus destructive infiltrates of BDC2.5 transgenic mice on the nonobese diabetic (NOD) versus C57BL/6.H-2(g(7)) genetic backgrounds. Natural kill...

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Main Authors: Poirot, Laurent, Benoist, Christophe, Mathis, Diane
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC419564/
https://ncbi.nlm.nih.gov/pubmed/15141080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402065101
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