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How punctual ablation of Foxp3(+) T cells unleashes an autoimmune lesion within the pancreatic islets
CD4(+)Foxp3(+) regulatory T cells (Tregs) are known to control the progression of autoimmune diabetes, but when, where and how they exert their influence in this context are questions still under vigorous debate. Exploiting a transgene encoding the human diphtheria toxin receptor, we punctually and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2998796/ https://ncbi.nlm.nih.gov/pubmed/19818653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.08.023 |
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