Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity

A combination of transcription factors, enhancers, and epigenetic marks determines the expression of the key transcription factor FoxP3 in regulatory T cells (Tregs). Adding an additional layer of complexity, the long noncoding RNA (lncRNA) Flicr (Foxp3 long intergenic noncoding RNA) is a negative r...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Zemmour, David, Pratama, Alvin, Loughhead, Scott M., Mathis, Diane, Benoist, Christophe
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410798/
https://ncbi.nlm.nih.gov/pubmed/28396406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700946114
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