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Imaging the emergence and natural progression of spontaneous autoimmune diabetes

Type 1 diabetes in the nonobese diabetic mouse stems from an infiltration of the pancreatic islets by a mixed population of immunocytes, which results in the impairment and eventual destruction of insulin-producing β-cells. Little is known about the dynamics of lymphocyte movement in the pancreas du...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mohan, James F., Kohler, Rainer H., Hill, Jonathan A., Weissleder, Ralph, Mathis, Diane, Benoist, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604023/
https://ncbi.nlm.nih.gov/pubmed/28839093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707381114
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