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Imaging the emergence and natural progression of spontaneous autoimmune diabetes

Type 1 diabetes in the nonobese diabetic mouse stems from an infiltration of the pancreatic islets by a mixed population of immunocytes, which results in the impairment and eventual destruction of insulin-producing β-cells. Little is known about the dynamics of lymphocyte movement in the pancreas du...

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Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Mohan, James F., Kohler, Rainer H., Hill, Jonathan A., Weissleder, Ralph, Mathis, Diane, Benoist, Christophe
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5604023/
https://ncbi.nlm.nih.gov/pubmed/28839093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1707381114
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