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Population dynamics of islet-infiltrating cells in autoimmune diabetes

Type-1 diabetes in the nonobese diabetic (NOD) mouse starts with an insulitis stage, wherein a mixed population of leukocytes invades the pancreas, followed by overt diabetes once enough insulin-producing β-cells are destroyed by invading immunocytes. Little is known of the dynamics of lymphocyte mo...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Magnuson, Angela M., Thurber, Greg M., Kohler, Rainer H., Weissleder, Ralph, Mathis, Diane, Benoist, Christophe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4321317/
https://ncbi.nlm.nih.gov/pubmed/25605891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423769112
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