Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ(10) deficiency

Coenzyme Q(10) (CoQ(10)) is essential for electron transport in the mitochondrial respiratory chain and antioxidant defense. The relative importance of respiratory chain defects, ROS production, and apoptosis in the pathogenesis of CoQ(10) deficiency is unknown. We determined previously that severe...

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Detaylı Bibliyografya
Asıl Yazarlar: Quinzii, Catarina M., López, Luis C., Gilkerson, Robert W., Dorado, Beatriz, Coku, Jorida, Naini, Ali B., Lagier-Tourenne, Clotilde, Schuelke, Markus, Salviati, Leonardo, Carrozzo, Rosalba, Santorelli, Filippo, Rahman, Shamima, Tazir, Meriem, Koenig, Michel, DiMauro, Salvatore, Hirano, Michio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Federation of American Societies for Experimental Biology 2010
Konular:
Research Communications
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996902/
https://ncbi.nlm.nih.gov/pubmed/20495179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-152728
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