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Highly conserved tyrosine stabilizes the active state of rhodopsin
Light-induced isomerization of the 11-cis-retinal chromophore in the visual pigment rhodopsin triggers displacement of the second extracellular loop (EL2) and motion of transmembrane helices H5, H6, and H7 leading to the active intermediate metarhodopsin II (Meta II). We describe solid-state NMR mea...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2993422/ https://ncbi.nlm.nih.gov/pubmed/21041664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009405107 |
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