Modulation of thermal stability can enhance the potency of siRNA

During RNA-induced silencing complex (RISC) assembly the guide (or antisense) strand has to separate from its complementary passenger (or sense) strand to generate the active RISC complex. Although this process was found to be facilitated through sense strand cleavage, there is evidence for an alter...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Addepalli, Haripriya, Meena, Peng, Chang G., Wang, Gang, Fan, Yupeng, Charisse, Klaus, Jayaprakash, K. Narayanannair, Rajeev, Kallanthottathil G., Pandey, Rajendra K., Lavine, Gary, Zhang, Ligang, Jahn-Hofmann, Kerstin, Hadwiger, Philipp, Manoharan, Muthiah, Maier, Martin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Synthetic Biology and Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978349/
https://ncbi.nlm.nih.gov/pubmed/20610434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq568
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados