Unique Gene-silencing and Structural Properties of 2′-F Modified siRNAs

Lignende værker

• Unexpected origins of the enhanced pairing affinity of 2′-fluoro-modified RNA
  af: Pallan, Pradeep S., et al.
  Udgivet: (2011)
• Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme
  af: Li, Feng, et al.
  Udgivet: (2007)
• 2′-Fluoro RNA Shows Increased Watson-Crick H-Bonding Strength and Stacking relative to RNA: Evidence from NMR and Thermodynamic Data
  af: Patra, Amritraj, et al.
  Udgivet: (2012)
• Modulation of thermal stability can enhance the potency of siRNA
  af: Addepalli, Haripriya, et al.
  Udgivet: (2010)
• Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver
  af: Akinc, Akin, et al.
  Udgivet: (2009)