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PAFc, a Key Player in MLL-rearranged Leukemogenesis

Recent studies identified an interaction between the Polymerase Associated Factor complex (PAFc) and Mixed Lineage Leukemia (MLL), including MLLrearranged oncoproteins. This interaction is critical for MLL transcriptional activity and MLL-rearranged leukemogenesis. Here, we discuss the potential mol...

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Bibliografiske detaljer
Main Authors: Tan, Jiaying, Muntean, Andrew G., Hess, Jay L.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965052/
https://ncbi.nlm.nih.gov/pubmed/21037944
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