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PAFc, a Key Player in MLL-rearranged Leukemogenesis

Recent studies identified an interaction between the Polymerase Associated Factor complex (PAFc) and Mixed Lineage Leukemia (MLL), including MLLrearranged oncoproteins. This interaction is critical for MLL transcriptional activity and MLL-rearranged leukemogenesis. Here, we discuss the potential mol...

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Detalhes bibliográficos
Main Authors: Tan, Jiaying, Muntean, Andrew G., Hess, Jay L.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965052/
https://ncbi.nlm.nih.gov/pubmed/21037944
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