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The PHD fingers of MLL block MLL fusion protein–mediated transformation

Chromosomal translocations involving the mixed lineage leukemia (MLL) gene are associated with aggressive acute lymphoid and myeloid leukemias. These translocations are restricted to an 8.3-kb breakpoint region resulting in fusion of amino terminal MLL sequences in frame to 1 of more than 60 differe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Muntean, Andrew G., Giannola, Diane, Udager, Aaron M., Hess, Jay L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597135/
https://ncbi.nlm.nih.gov/pubmed/18796627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-134056
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