The PHD fingers of MLL block MLL fusion protein–mediated transformation

Chromosomal translocations involving the mixed lineage leukemia (MLL) gene are associated with aggressive acute lymphoid and myeloid leukemias. These translocations are restricted to an 8.3-kb breakpoint region resulting in fusion of amino terminal MLL sequences in frame to 1 of more than 60 differe...

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Detaylı Bibliyografya
Asıl Yazarlar: Muntean, Andrew G., Giannola, Diane, Udager, Aaron M., Hess, Jay L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2008
Konular:
Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597135/
https://ncbi.nlm.nih.gov/pubmed/18796627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-134056
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