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The PHD fingers of MLL block MLL fusion protein–mediated transformation
Chromosomal translocations involving the mixed lineage leukemia (MLL) gene are associated with aggressive acute lymphoid and myeloid leukemias. These translocations are restricted to an 8.3-kb breakpoint region resulting in fusion of amino terminal MLL sequences in frame to 1 of more than 60 differe...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597135/ https://ncbi.nlm.nih.gov/pubmed/18796627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-134056 |
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