African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA

African swine fever virus (ASFV) encodes an AP endonuclease (pE296R) which is essential for virus growth in swine macrophages. We show here that the DNA repair functions of pE296R (AP endonucleolytic, 3′ → 5′ exonuclease, 3′-diesterase and nucleotide incision repair (NIR) activities) and DNA binding...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Redrejo-Rodríguez, Modesto, Ishchenko, Alexander A., Saparbaev, Murat K., Salas, María L., Salas, José
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2009
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958311/
https://ncbi.nlm.nih.gov/pubmed/19464038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.04.021
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge