A unique DNA-binding mode of African swine fever virus AP endonuclease

African swine fever virus (ASFV) is highly contagious and can cause lethal disease in pigs. ASFV is primarily replicated in the cytoplasm of pig macrophages, which is oxidative and caused constant damage to ASFV genome. ASFV AP endonuclease (AsfvAP) catalyzes DNA cleavage reaction at the abasic site...

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Vydáno v:Cell Discov
Hlavní autoři: Chen, Yiqing, Chen, Xi, Huang, Qi, Shao, Zhiwei, Gao, Yanqing, Li, Yangyang, Yang, Chun, Liu, Hehua, Li, Jixi, Wang, Qiyao, Ma, Jinbiao, Zhang, Yong-Zhen, Gu, Yijun, Gan, Jianhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076025/
https://ncbi.nlm.nih.gov/pubmed/32194979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-020-0146-2
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