Unique 5′-P recognition and basis for dG:dGTP misincorporation of ASFV DNA polymerase X

African swine fever virus (ASFV) can cause highly lethal disease in pigs and is becoming a global threat. ASFV DNA Polymerase X (AsfvPolX) is the most distinctive DNA polymerase identified to date; it lacks two DNA-binding domains (the thumb domain and 8-KD domain) conserved in the homologous protei...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Chen, Yiqing, Zhang, Jing, Liu, Hehua, Gao, Yanqing, Li, Xuhang, Zheng, Lina, Cui, Ruixue, Yao, Qingqing, Rong, Liang, Li, Jixi, Huang, Zhen, Ma, Jinbiao, Gan, Jianhua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330486/
https://ncbi.nlm.nih.gov/pubmed/28245220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002599
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